Most beautiful Island that we've ever seen. We took a cheap tour from Vinales to this Island, and were quite surprised to get an old american car, which we shared with 3 other travellers.
We visited the National Park Alejandro de Humboldt with a daytour from Baracoa. We walked the 7km long trail called "Balcon de Iberia".
During dry season from november to april, start the hike early. Shoulder season May and June, showers may occur and it is easier to find a nice casa. July and August are the Cuban school holiday.
Deep into the Sierra Maestra mountains (near Bayamo) you can walk the trail to the historical site of La Comandancia de la Plata. From Bayamo you'll need a car or a taxi to come to Santo Domingo.
Start early in the dry season (from november till april) and beginning of the rainy season until end of June. Shoulder season May and June, showers may occur. July and August are the Cuban school holiday.